Department Colloquium: Tuesday, October 18, 2022 - Prediction in Immune Repertoires

Event Date: 

Tuesday, October 18, 2022 - 3:45pm

Event Date Details: 

This event will be in-person and on Zoom.

Event Location: 

  • Broida 1640 and Zoom
  • Physics Department Colloquium

This event will be in-person and on Zoom.

Prediction in Immune Repertoires

Aleksandra Walczak, ENS, Paris

Living systems often attempt to calculate and predict the future state of the environment.  Given the stochastic nature of many biological systems how is that possible? I will show that even a system as complicated as the immune system has reproducible outcomes. Yet predicting the future state of a complex environment requires weighing the trust in new observations against prior experiences. In this light, I will present a view of the adaptive immune system as a dynamic Bayesian machinery that updates its memory repertoire by balancing evidence from new pathogen encounters against past experience of infection to predict and prepare for future threats.


Aleksandra Walczak, ENS, Paris